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Bronchial asthma
Bronchial asthma is a disease accompanying humanity for a long time. The first known description of it comes from 1500 years BC (Ebersa papyrus, Egypt). This is one of the most common chronic respiratory diseases. Asthma occurs in all ages, in the West among the adults about 5% of ill persons.
Overreactive bronchitis and chronic inflammation.
Bronchial asthma is a disease characterized by excessive bronchial reactivity in a variety of incentives (discussed below). The reason for the excess reactivity is a chronic inflammation of the airways in which many cells participate (mastocyty, eosinophils, T lymphocytes) and substances released by them (histamine, leukotrieny and others).
Chronic inflammation and bronchial nadreaktywność to specific stimuli are the cause of shrinkage bronchitis, excess mucus production and swelling in oskrzelach bronchial mucous membrane - leads to a limitation of the air by the onset of symptoms and bronchial asthma. Chronic, long-untreated inflammation leads to the conversion bronchitis - fibrosis, smooth muscle overgrowth in time may cause the obturacja (narrowing of bronchi) is irreversible.
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